Thursday, March 21
13:00‐15:00 Registration and accommodation
14:30 Coffee
15:00 Opening of XVI Discussions and 3rd User Meeting of CIISB, Vladimír Sklenář
15:15‐16:45 Session I, Chair: Vladimír Sklenář
Zdeněk Futera, University College London: Electric Conductivity of Multi-Heme Proteins, 30’
Miroslav Kloz, ELI Beamlines:Femtosecond vibration spectroscopy of unprotonated retinal in a UV absorbing rhodopsin biological photoreceptor
Irena Kratochvílová, Institute of Physics, CAS: Critical defects in cryopreserved cell nuclei: DNA structure changes
Petr Kulhánek, Masaryk University: Flexibility of DNA mismatches and its implication for mismatch recognition
16:45-17:15 Coffee break
17:15-18:15 Invited speaker
Marjolein Thunnissen, Lund University: Structural Biology at the diffraction limited synchrotron source MAX IV
18:15 Dinner
Friday, March 22
7:30-9:00 Breakfast
9:00-10:35 Session II, Chair: Rostislav Škrabana
Josef Houser, Masaryk University: Comparative structural analysis of lectin family from Photorhabdus spp. (CIISB User meeting)
Martin Marek, Masaryk University: Structural basis of histone deacetylase 8 (HDAC8) selective inhibition
Zora Nováková, Institute of Biotechnology, CAS: New antibody-based tools for prostate cancer imaging and therapy
Jakub Ptáček, Institute of Biotechnology, CAS: Design and biological and structural characterization of novel HDAC6-specific inhibitors
Christin Reuter, Jena Bioscience GmbH: Crystal growth to data collection made easy, 15’
10:35-11:00 Coffee break
11:00-12:45 Session III, Chair: Jiří Pavlíček
Tomasz Kabzinski, Masaryk University: Connecting 5’ to 3’ activities: Interaction between Rtt103p and Trf4p, 30’ (Student talk)
Vojtěch Zapletal, Masaryk University: Quantitative conformational analyses of intrinsically disordered proteins: nuclear magnetic resonance spectroscopy and small-angle X-ray scattering in action (Student talk)
Evžen Bouřa, Institute of Organic Chemistry and Biochemistry, CAS: Structural analysis of positive sense +RNA polymerases
Jakub Svoboda, Institute of Biotechnology, CAS: Crystal structure and biophysical characterization of selected REP sequences (CIISB User meeting, student talk)
Pawel Kania, Nano Temper Technologies: When affinity matters, 15’
13:00-14:30 Lunch
15:30-16:00 Coffee
16:00-17:35 Session IV, Chair: Ivana Kutá Smatanová
Imrich Barák, Institute of Molecular Biology, SAS: Asymmetric cell division during sporulation in Bacillus subtilis, 30’
Michal Buša, Institute of Organic Chemistry and Biochemistry, CAS: Evolutionary upgrade of stefins for secretion in parasites, (Student talk)
Edward Curtis, Institute of Organic Chemistry and Biochemistry, CAS: A GTP-dependent switch that controls G-quadruplex multimer formation
Angelika Scheiflinger-Latal, Anton Paar GmbH: Insights into the structure and conformation of biomolecules to understand their biological function for new drug systems using SAXS in the Laboratory, 15’
Radek Kužel, Faculty of Mathematics and Physics, CUNI: IUCr 2020, 10’
17:35-18:00 General Assembly of the Czech Society for Structural Biology
Meeting will be held in the Czech and/or Slovak languages
1. Volba zapisovatele; 2. Schválení programu; 3. Výroční zpráva Rady ČSSB o činnosti a hospodaření;
4. Zpráva revizní komise; 5. Schválení výroční zprávy Rady ČSSB o činnosti a hospodaření;
6. Infrastruktury se vztahem ke strukturní biologii, přístupy, financování, vývoj Instructu;
7. Změna sídla ČSSB v souvislosti se zprovozněním centra Biocev – vývoj 8. Různé
18:00-19:30 Dinner
19:30-22:00 Poster session
Saturday, March 23
7:30-9:00 Breakfast
9:00-10:30 Session V, Chair: Vojtěch Spiwok
Pavol Bárdy, Masaryk University: Structure and DNA delivery mechanism of gene transfer agent of Rhodobacter capsulatus, 30’ (CIISB User meeting, student talk)
David Buchta, Masaryk University, CEITEC: Genome release of Echovirus 18 (Student talk)
Dominik Hrebík, Masaryk University, CEITEC: Cryo-EM Structure of Bacteriophage P68: From Head to Tail (CIISB User meeting, student talk)
Tibor Füzik, Masaryk University, CEITEC: Structural study of human enterovirus 70 using cryo-electron microscopy (CIISB User meeting)
10:30-11:00 Coffee break
11:00-12:20 Session VI, Chair: Imrich Barák
Jiří Pavlíček, Institute of Biotechnology, CAS: Centre of Molecular Structure in BIOCEV – Information and Updates (CIISB User meeting)
Michaela Procházková, Masaryk University, CEITEC: Structure of Leishmania RNA virus 1 (CIISB User meeting)
Andrea Schenkmayerová, International Clinical Research Center, FNUSA: Laboratory evolution reveals structural elements driving enzyme evolvability
Radim Nencka, Institute of Organic Chemistry and Biochemistry, CAS: With or without you: Structure vs. ligand-based drug design
12:20-12:30 Student presentations awards, concluding remarks
12:30 Lunch & departure