Czech Society for Structural Biology
Česká společnost pro strukturní biologii



The Czech Society
for Structural Biology
(Česká společnost
pro strukturní biologii

Videnska 1083
CZ-142 20 Prague
Czech Republic

CSSB@structbio.org
VAT number: 0022869433
account num.: 2300076583/2010
IBAN: CZ2820100000002300076583
SWIFT/BIC: FIOBCZPPXXX

Programme of XVII Discussions in Structural Molecular Biology and 4th User Meeting of CIISB

 

All talks are 20 minutes long unless indicated otherwise. All times are INCLUDING
discussion.

 

Thursday, March 19

12:00–14:00 Registration and accommodation, coffee

14:00 Opening of XVII Discussions and 4th User Meeting of CIISB (Jan Dohnálek, Vladimír Sklenář)

14:15–15:45 Session I Chair person: Jiří Pavlíček

Pavlína Řezáčová, Institute of Organic Chemistry and Biochemistry, Czech Academy of Science

Structural studies of SorC family of transcriptional regulators 30’

Jan Dohnálek, Institute of Biotechnology, Czech Academy of Sciences

Unusual covalent bond between Trp and His in Bilirubin oxidase

(CIISB User meeting)

Martin Malý, Institute of Biotechnology, Czech Academy of Sciences

Advantages of complete cross-validation in paired refinement

(Student talk)

Jan Stránský, Institute of Biotechnology, Czech Academy of Sciences

Updates to instrumentation in the Centre of Molecular Structure in BIOCEV

(CIISB User meeting)

15:45–16:15 Coffee break

16:15–18:20 Session II Chair person: Lukáš Žídek

Bohdan Schneider, Institute of Biotechnology, Czech Academy of Sciences

Structural alphabet for structural analysis of nucleic acids

Martin Gajarský, CEITEC, Masaryk University

Phylogenetically diverged structural motifs in telomeric DNA

(Student talk, CIISB User meeting)

Kateřina Beková, CEITEC, Masaryk University

Formation propensity of pseudo-circular G-hairpins

(Student talk)

Aliaksei Chareshneu, CEITEC, Masaryk University

NACHRDB: solving the puzzle of structure-function relationships in nicotinic acetylcholine receptors (nAChRs)

(Student talk)

Michal H. Kolář, University of Chemistry and Technology

Large-scale atomistic simulations of the ribosome and its exit tunnel

Piotr Wardega, NanoTemper Technologies Sp. z o.o.

When protein stability matters 15’

Radek Kužel, Faculty of Mathematics and Physics, Charles University

IUCr 2020 10’

18:30 Dinner, sponsored by Bruker AXS

 

Friday, March 20

7:30–9:00 Breakfast

9:00–10:20 Session III Chair person: Vladimír Sklenář

Klára Kohoutová, Faculty of Science, Charles University

Modulating FOXO3 Transcriptional Activity by Small, DBD-binding Molecules

(Student talk)

Daniel Krafčík, CEITEC, Masaryk University

Investigation into G4–Ligand Complex in Living Human Cells Using In-cell NMR Spectroscopy

(Student talk, CIISB User meeting)

Vanda Lux, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences

Molecular mechanism of LEDGF/p75 dimerization

Pavlína Víšková, CEITEC, Masaryk University

Study of the i-motif stability during the cell cycle progression by in cell NMR spectroscopy

(Student talk, CIISB User meeting)

10:20–10:50 Coffee break

10:50–12:25 Session IV Chair person: Tomáš Obšil

Pavol Bárdy, CEITEC, Masaryk University

The story of Rhodobacter capsulatus gene transfer agent: Virus, organelle or both?

(Student talk, CIISB User meeting)

Marta Šiborová, CEITEC, Masaryk University

Structure of bacteriophage SU10

(Student talk, CIISB User meeting)

David Buchta, CEITEC, Masaryk University

Binding of neoFc receptor traps intermediate of pocket factor expulsion from echovirus 18

(Student talk, CIISB User meeting)

Sebastian Zoll, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences

Invariant surface glycoproteins of trypanosomes as targets for structure-guided drug and vaccine design

Florence Husada, Thermo Fisher Scientific

How Cryo-EM is revolutionizing structural biology complexes after the "resolution revolution" 15’

12:30–14:00 Lunch

14:00–15:00 CIISB Executive committee

15:00–16:00 Session V Chair person: Pavlína Řezáčová

Kateřina Slánská, Faculty of Science, Masaryk University

Analysis and prediction of protein solubility

(Student talk)

Petr Louša, CEITEC, Masaryk University

How phosphorylation impacts 14-3-3ζ dimerization

(Student talk)

Simona Lenhartová, Biomedical Research Center, Slovak Academy of Sciences

Preliminary characterization of human CD160 and the influence of viral N-linked

glycosylation related to this immune inhibitory pathway

(Student talk)

16:00–16:20 Coffee (short)

16:20–17:50 Session VI Chair person: Jiří Vondrášek

Martin Lepšík, Centre de recherches sur les macromolécules végétales, CNRS

Calcium Bridging between Carbohydrates and Lectins: A Difficult Case for Classical Molecular Dynamics 30’

Francesco Luca Falginella, CEITEC, Masaryk University

Elucidating Phospholipid Membrane Binding of DEP domain in the Wnt Signaling Pathway

(Student talk)

Dalibor Trapl, University of Chemistry and Technology

Atomistic simulation of carbohydrate-protein complex formation: Hevein-32 domain

(Student talk)

Zdeněk Futera, Faculty of Science, University of South Bohemia

Electron Transfer Kinetics in Cytochrome C

18:00–19:00  General Assembly of the Czech Society for Structural Biology

Meeting will be held in the Czech and/or Slovak languages

1. Volba zapisovatele;
2. Schválení programu;
3. Volba Rady ČSSB - seznam kandidátů;
4. Výroční zpráva Rady ČSSB o činnosti a hospodaření;
5. Zpráva revizní komise;
6. Schválení výroční zprávy Rady ČSSB o činnosti a hospodaření;
7. Infrastruktury se vztahem ke strukturní biologii
8. Vyhlášení výsledků voleb
9. Různé

19:00–20:00 Dinner

(Meeting of the previous and new Council of CSSB)

20:00–22:00 Poster session

 

Saturday, March 21

7:30–9:00 Breakfast

9:00–10:40 Session VII Chair person: Cyril Bařinka

Josef Lazar, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences

Fluorescent proteins as molecular antennas: structure and directionality

Martin Marek, Loschmidt Laboratories, Masaryk University

Structural Basis for Engineered Thermostability in Haloalkane Dehalogenases

Ladislav Bumba, Institute of Microbiology, Czech Academy of Sciences

Structure-function aspects of the T1SS-mediated secretion of large RTX proteins

Tereza Skálová, Institute of Biotechnology, Czech Academy of Sciences

Crystal structure of heme-based oxygen sensor AfGcHK in complex with imidazole

(CIISB User meeting)

Josef Houser, CEITEC, Masaryk University

O-methylated saccharides as a neglected target for Photorhabdus spp. Lectins

10:40–11:10 Coffee break

11:10–12:30 Session VIII Chair person: Imrich Barák

Edward Curtis, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences

Making light with DNA

Robert Vácha, CEITEC, Masaryk University

Effect of Helical Kink in Antimicrobial Peptides on Membrane Pore Formation

David Kopečný, Faculty of Science, Palacký University

Urea-derived inhibitors of cytokinin oxidase/dehydrogenase for agricultural applications

Miroslav Kloz, ELI Beamlines, Institute of Physics, Czech Academy of Sciences

Comparative ultrafast spectroscopy and structural analysis of OCP1 and OCP2 protein from Tolypothrix

12:30–12:45 Evaluation of student presentations, prizes, concluding remarks

13:00 Lunch & departure