Thursday, March 19
12:00–14:00 Registration and accommodation, coffee
14:00 Opening of XVII Discussions and 4th User Meeting of CIISB (Jan Dohnálek, Vladimír Sklenář)
14:15–15:45 Session I Chair person: Jiří Pavlíček
Pavlína Řezáčová, Institute of Organic Chemistry and Biochemistry, Czech Academy of Science
Structural studies of SorC family of transcriptional regulators 30’
Jan Dohnálek, Institute of Biotechnology, Czech Academy of Sciences
Unusual covalent bond between Trp and His in Bilirubin oxidase
(CIISB User meeting)
Martin Malý, Institute of Biotechnology, Czech Academy of Sciences
Advantages of complete cross-validation in paired refinement
(Student talk)
Jan Stránský, Institute of Biotechnology, Czech Academy of Sciences
Updates to instrumentation in the Centre of Molecular Structure in BIOCEV
(CIISB User meeting)
15:45–16:15 Coffee break
16:15–18:20 Session II Chair person: Lukáš Žídek
Bohdan Schneider, Institute of Biotechnology, Czech Academy of Sciences
Structural alphabet for structural analysis of nucleic acids
Martin Gajarský, CEITEC, Masaryk University
Phylogenetically diverged structural motifs in telomeric DNA
(Student talk, CIISB User meeting)
Kateřina Beková, CEITEC, Masaryk University
Formation propensity of pseudo-circular G-hairpins
(Student talk)
Aliaksei Chareshneu, CEITEC, Masaryk University
NACHRDB: solving the puzzle of structure-function relationships in nicotinic acetylcholine receptors (nAChRs)
(Student talk)
Michal H. Kolář, University of Chemistry and Technology
Large-scale atomistic simulations of the ribosome and its exit tunnel
Piotr Wardega, NanoTemper Technologies Sp. z o.o.
When protein stability matters 15’
Radek Kužel, Faculty of Mathematics and Physics, Charles University
IUCr 2020 10’
18:30 Dinner, sponsored by Bruker AXS
Friday, March 20
7:30–9:00 Breakfast
9:00–10:20 Session III Chair person: Vladimír Sklenář
Klára Kohoutová, Faculty of Science, Charles University
Modulating FOXO3 Transcriptional Activity by Small, DBD-binding Molecules
(Student talk)
Daniel Krafčík, CEITEC, Masaryk University
Investigation into G4–Ligand Complex in Living Human Cells Using In-cell NMR Spectroscopy
(Student talk, CIISB User meeting)
Vanda Lux, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences
Molecular mechanism of LEDGF/p75 dimerization
Pavlína Víšková, CEITEC, Masaryk University
Study of the i-motif stability during the cell cycle progression by in cell NMR spectroscopy
(Student talk, CIISB User meeting)
10:20–10:50 Coffee break
10:50–12:25 Session IV Chair person: Tomáš Obšil
Pavol Bárdy, CEITEC, Masaryk University
The story of Rhodobacter capsulatus gene transfer agent: Virus, organelle or both?
(Student talk, CIISB User meeting)
Marta Šiborová, CEITEC, Masaryk University
Structure of bacteriophage SU10
(Student talk, CIISB User meeting)
David Buchta, CEITEC, Masaryk University
Binding of neoFc receptor traps intermediate of pocket factor expulsion from echovirus 18
(Student talk, CIISB User meeting)
Sebastian Zoll, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences
Invariant surface glycoproteins of trypanosomes as targets for structure-guided drug and vaccine design
Florence Husada, Thermo Fisher Scientific
How Cryo-EM is revolutionizing structural biology complexes after the “resolution revolution” 15’
12:30–14:00 Lunch
14:00–15:00 CIISB Executive committee
15:00–16:00 Session V Chair person: Pavlína Řezáčová
Kateřina Slánská, Faculty of Science, Masaryk University
Analysis and prediction of protein solubility
(Student talk)
Petr Louša, CEITEC, Masaryk University
How phosphorylation impacts 14-3-3ζ dimerization
(Student talk)
Simona Lenhartová, Biomedical Research Center, Slovak Academy of Sciences
Preliminary characterization of human CD160 and the influence of viral N-linked
glycosylation related to this immune inhibitory pathway
(Student talk)
16:00–16:20 Coffee (short)
16:20–17:50 Session VI Chair person: Jiří Vondrášek
Martin Lepšík, Centre de recherches sur les macromolécules végétales, CNRS
Calcium Bridging between Carbohydrates and Lectins: A Difficult Case for Classical Molecular Dynamics 30’
Francesco Luca Falginella, CEITEC, Masaryk University
Elucidating Phospholipid Membrane Binding of DEP domain in the Wnt Signaling Pathway
(Student talk)
Dalibor Trapl, University of Chemistry and Technology
Atomistic simulation of carbohydrate-protein complex formation: Hevein-32 domain
(Student talk)
Zdeněk Futera, Faculty of Science, University of South Bohemia
Electron Transfer Kinetics in Cytochrome C
18:00–19:00 General Assembly of the Czech Society for Structural Biology
Meeting will be held in the Czech and/or Slovak languages
- Volba zapisovatele;
- Schválení programu;
- Volba Rady ČSSB – seznam kandidátů;
- Výroční zpráva Rady ČSSB o činnosti a hospodaření;
- Zpráva revizní komise;
- Schválení výroční zprávy Rady ČSSB o činnosti a hospodaření;
- Infrastruktury se vztahem ke strukturní biologii
- Vyhlášení výsledků voleb
- Různé
19:00–20:00 Dinner
(Meeting of the previous and new Council of CSSB)
20:00–22:00 Poster session
Saturday, March 21
7:30–9:00 Breakfast
9:00–10:40 Session VII Chair person: Cyril Bařinka
Josef Lazar, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences
Fluorescent proteins as molecular antennas: structure and directionality
Martin Marek, Loschmidt Laboratories, Masaryk University
Structural Basis for Engineered Thermostability in Haloalkane Dehalogenases
Ladislav Bumba, Institute of Microbiology, Czech Academy of Sciences
Structure-function aspects of the T1SS-mediated secretion of large RTX proteins
Tereza Skálová, Institute of Biotechnology, Czech Academy of Sciences
Crystal structure of heme-based oxygen sensor AfGcHK in complex with imidazole
(CIISB User meeting)
Josef Houser, CEITEC, Masaryk University
O-methylated saccharides as a neglected target for Photorhabdus spp. Lectins
10:40–11:10 Coffee break
11:10–12:30 Session VIII Chair person: Imrich Barák
Edward Curtis, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences
Making light with DNA
Robert Vácha, CEITEC, Masaryk University
Effect of Helical Kink in Antimicrobial Peptides on Membrane Pore Formation
David Kopečný, Faculty of Science, Palacký University
Urea-derived inhibitors of cytokinin oxidase/dehydrogenase for agricultural applications
Miroslav Kloz, ELI Beamlines, Institute of Physics, Czech Academy of Sciences
Comparative ultrafast spectroscopy and structural analysis of OCP1 and OCP2 protein from Tolypothrix
12:30–12:45 Evaluation of student presentations, prizes, concluding remarks
13:00 Lunch & departure