Center for Biomolecules and Complex Molecular Systems,
Institute of Physical Biology, University of Southern Bohemia, Ceske Budejovice
Czech and Slovak Crystallographic Association
Czech FOBIA (Free&OPen Bioinformatic Association)
VIth Discussions in Structural Molecular Biology and Bioinformatics
Nové Hrady, March 29 – 31 2007
Program of the VIth Discussions (March 29 – 31, 2007)
Thursday, March 29
12:00 – 14:00 Registration
14:15 – 14:20 Introductory remarks
14:20 – 15:20 Lecture session I, chairperson P. Rezacova
Pavel Plevka: The Structure of Ryegrass Mottle Virus
Petr Kolenko: Crystallographic studies of intermolecular interactions of Fc-fragment of immunoglobulin
Michal Kolar: Protein as a Flexible Structure: Case Study of the HIV Protease
15:20 – 15:30 Coffee break
15:30 – 16:20 Lecture session II, chairperson P. Rezacova
Jiri Brynda: TLS analysis of antibody structure shows stabilization by epitope binding
Tomas Obsil: Interaction of DNA-binding domain of transcription factor FoxO4 with DNA (*)
16:20 – 16:30 Coffee break
16:30 – 17:05 Plenary lecture I, chairperson B. Schneider
Filip Lankas: Structural mechanics of DNA: from atomic scale to bioinformatics
17:05 – 17:15 Coffee break
17:15 – 17:50 Plenary lecture II, chairperson J. Hasek
Tomas Polivka: Time-resolved structural dynamics – A challenge for future
17:50 – 18:00 Coffee break
18:00 – 19:00 Concert of violin duo Lukas Kuta & Vaclav Polivka
J.M Leclair, J.S. Bach, S. Prokofjev and others
Detailed program will be available at the time of registration
19:00 – 22:30 Banquet
Friday, March 30
7:00 – 8:45 Breakfast
9:00 – 10:50 Lecture Session III, chairperson R. Hrabal
Lukas Zidek: Orientational restraints in NMR structure determination (*)
Pavel Srb: Is local flexibility of M-PMV matrix protein related to its binding affinity with a molecular motor? (*)
Richard Stefl: RNA recognition by the ADAR2 dsRBMs: a 50 kDa protein-RNA complex by NMR (*)
Vladimir Sychrovsky: Calculation of Scalar Couplings in the Backbone of Nucleic Acid
10:50 – 11:00 Coffee break
11:00 – 12:20 Lecture session IV, chairperson L. Zidek
Zuzana Vokacova: Theoretical NMR Study of Watson-Crick/Sugar Edge RNA Base Pair Family
Jaroslav Burda: Computational study on spectral properties of the selected pigments from various photosystems; structure–transition energy relationship
Jiri Mrazek: Electronic structure of the non-heme iron center in photosynthetic apparatus of plants and bacteria. Computational DFT study
Tomas Zimmermann: Computational study of cysteine and methionine interaction with platinum(II) complexes in water
12:30 – 14:00 Lunch
14:00 – 15:20 Lecture Session V, chairperson J. Paces
Jan Adam: Computational chemistry as a helpful tool for structure-functional study and correlation, en route to protein engineering
Rudiger Ettrich: Structure and dynamics of the oxygen evolving complex of photosystem II: Role of the N-terminal loop of PsbQ
Ondrej Sulak: New approaches to structure and function studies of RS20L lectin from Ralstonia solanacearum
Navnit Mishra: Computational Studies on PA-IIL Lectin-Carbohydrate Interactions
15:20 – 15:30 Coffee break
15:30 – 17:25 Lecture session VI, chairperson I. Kratochvilova
Bohdan Schneider: Conformational space of nucleic acids (*)
Dana Nachtigallova: Electronic coupling in the excited electronic state of stacked DNA bases (*)
Dalibor Stys: Mathematically-based studies of complex systems in physics, mathematics, chemistry, biology, economy and politics in Nove Hrady in the first half of 19th century and at the beginning of 21st century
Radomir Kuzel: Forthcoming meetings of the Czech and Slovak Crystallographic Association – short information. Correct typesetting of papers – general rules on correct typing and writing references. Future evaluation of publications.
Peter Sebo: Progress in building of the Biotechnology center in Vestec
17:30 – 18:30 Dinner
19:00 – 22:00 Poster session
Saturday, March 31
7:00 – 9:10 Breakfast
9:15 – 10:15 Lecture session VII, chairperson R. Zika
Irena Kratochvilova: Thin molecular electronic devices
Jan Paces: Tool for ChIPonChip analysis
Eva Brumovska: Structural and functional characterization of human protein kinase CKI epsilon
10:15 – 10:30 Coffee break
10:30 – 11:40 Lecture session VIII, chairperson T. Obsil
Jan Dohnalek: Subtilases and metal binding – the weak binding site of subtilisins revisited
Jindrich Hasek: Ligand docking to biochemical targets – crystallography and modeling
Pavlina Rezacova: Structural studies of the repressor CggR from Bacillus subtilis (*)
11:40 – 11:41 Concluding remarks
12:00 – 14:00 Lunch
Thirty minute talks are labeled by an asterix, (*), other talks have a limit of 20 minutes. All times include discussion.