Instruct-ERIC workshop on Computational Approaches in Integrative Structural Biology

Dates: October 8–10, 2019

Venue: Institute of Biotechnology of the Czech Academy of Sciences, Research centre Biocev, Prumyslova 595, 25250 Vestec near Prague, Czech Republic

Aim:The course will be focused on the growing need to combine computational tools in structural biology projects. The main aims are in providing deeper insights in the computational approaches for selected techniques and then to build on the good foundations and cover also integration of data coming from various structural approaches, e.g. mass spec, NMR and other restraints used in structural analysis, together with SAXS envelopes and cryoEM maps applied in and with crystallographic analysis, use of biophysics to enhance/help in structure analysis, etc. Practical experience with selected structural biology techniques will be providedand tutorials on use of some computational tools will be given.

Link: http://www.ibt.cas.cz/sd/udalosti/kalendar/191008-Instruct-ERIC-workshop.html

Posted on Categories News

iNEXT Workshop on Integrated methodologies and approaches for structural biology

Structural biology supplies data allowing insight into the molecular architecture of a cell at the atomic resolution. iNEXT, a consortium funded by the Horizon2020 program, offers European researchers access to a wide range of advanced structural biology technologies to study the structure and function of biological macromolecules and their assemblies.

The aim of the iNEXT workshop Integrated methodologies and approaches for structural biology is to provide a comprehensive overview of the state-of the-art progress of integrative methodologies to existing and potential users of iNEXT facilities. Nineteen prominent speakers will report on recent advances and developments in nuclear magnetic resonance (NMR), x-ray diffraction, small-angle x-ray scattering (SAXS), cryo electron microscopy and tomography (cryo-EM and cryo-ET), and computational structural biology. Applications of recently developed methodologies to elucidate structure and function of complex cellular components and molecular machineries will be presented. The workshop is open to all PhD students, postdoctoral fellows, and researchers at no cost.

http://inext-workshop-2019.ceitec.cz/

Posted on Categories News

prof. Kay Diederichs: Taxonomy of errors and mistakes in X-ray crystallography

České vysoké učení technické v Praze, Fakulta jaderná a fyzikálně inženýrská a Česká společnost pro strukturní biologii vás zve na přednášku
prof. Kay Diederichs (Univerzita v Kostnici)
Taxonomy of errors and mistakes in X-ray crystallography
Přednáška se bude konat ve PONDĚLÍ dne 12.11.2018 od 10:00 hodin v místnosti ATRIUM v Břehové ulici (FJFI ČVUT, Břehová 7, Praha 1), po přednášce bude následovat představení programů XDS a XDSgui.
Organizační výbor: Jaroslav Bielčík (KF), Ivan Richter (KFE), Tomáš Bílý (KJR), Pavel Šťovíček (KM).

Abstract
Taxonomy of errors and mistakes in X-ray crystallography Crystallography lets us visualize the molecules of life – more than 130.000 structures in the PDB attest to that. But all that glitters is not gold. Some of the concepts developed decades ago now need revision. For example, analysis of crystallographic data quality is still somewhat fixated on values of Rmerge (also called Rsym), and the distinction between accuracy and precision, as well as indicators of unmerged data precision and those of merged data precision is only now starting to be accepted in the community.

Posted on Categories News