Frontiers in targeted modulation of protein function

Workshop organized jointly by the Weizmann Institute of Science and the Institute of Biotechnology CAS

BIOCEV, Vestec, Czech Republic
November 28 2016, 9:30


You are cordially invited to talks by three prominent scientists from the Weizmann Institute of Science held at the BIOCEV, Prumyslova 595, Vestec on November 28 from 9:30 o’clock.

  • Tamar Unger: The pipeline of protein production towards ‘well-behaved’ purified protein
  • Rina Rosenzweig: The many things we can learn about chaperone-substrate interactions through NMR
  • Ron Diskin: Structural Studies of Viral Glycoproteins


BIOCEV can be reached easily by car or by public transport, BUS 326 from Opatov, METRO C.

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Third Instruct Biennial Structural Biology Meeting

The third Instruct Biennial Structural Biology Meeting will take place in Brno, Czech Republic the 25-26th of May 2017. Brno is the city of Johann Gregor Mendel, a founder of modern genetics and one of the first scientists who applied multidisciplinary approach to explain his observations. Social programme of the meeting will include visit of the Mendel’s Museum and dinner at the Augustinian Abbey, where Johann Gregor Mendel worked and lived.

The inaugural Instruct Structural Biology Meeting at Heidelberg in 2013 successfully showcased integrative structural biology and its impact on biological research and biomedicine. The second Biennial took place in Florence in 2015 continuing the integrative line with an increased focus on innovation. This new edition will include sessions that represent recent structural biology highlights, emerging methods and technologies and results of biomedical importance.

Instruct Biennial Structural Biology Registrations open

Confirmed speakers includes:

Speaker NameInstitute
Dave StuartInstruct/University of Oxford
Albert HeckUtrecht University
Leemor Joshua-TorCold Spring Harbor Laboratory
Helen SaibilBirkbeck College London
Masahide KikkawaUniversity of Tokio
Juli FeigonUCLA
Michael SattlerTU Munich
Kristina Djinovic-CarugoUniversity of Vienna
Babis KalodimosUniversity of Minnesota
Richard SteflMasaryk University
Janusz BrujnickiInternational Institute of Molecular and Cell Biology
Andrew CarterMRC Laboratory of Molecular Biology, Cambridge
Thijn BrummelkampNetherland Cancer Institute
James NaismithThe University St Andrews
Raymond StevensUSC Dornsife
Petr LeimanUniversity of Texas Medical Branch

Upcoming submission opportunities/deadlines include:

Abstract submission: March 1

Registration closing: April 1

Student fellowships: March 1

We look forward to seeing you in Brno

The Instruct Operations Team

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FEBS Advanced Course: Ligand-binding Theory and Practice

FEBS Advanced Course: Ligand-binding Theory and Practice will take place in Nové Hrady on July 3 – July 10, 2016 (application deadline: April 1, 2016). This course provides training in the theoretical and practical principles of ligand binding. It offers participants the possibility to analyse their own macromolecular interaction systems using contemporary advanced methods including surface plasmon resonance, isothermal titration calorimetry, UV-vis and fluorescence spectroscopies, and microscale thermophoresis. The design, execution, and interpretation of these experiments will be guided by expert tutors. Additional lecturers will discuss other contemporary methods used in experimental studies of ligand binding, and current views on the phenomenon of allostery.

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Advanced Methods in Macromolecular Crystallization VII

Advanced Methods in Macromolecular Crystallization VII
the 2nd FEBS practical crystallization course in middle EU co-sponsored by INSTRUCT
The course is intended for undergraduate (5th year) and postgraduate students and postdocs with an interest in macromolecular crystallization. Number of participant is limited to 35.
The crystallization of biological macromolecules is still poorly understood and, as a consequence, success of the common trial-and-error experiments is not predictable. On the other hand, more rational approaches have been developed in the past few years and prospects for the science of crystallogenesis are in fact good. Many of the new approaches are based on an improved theoretical insight into the processes of nucleation and crystal growth.
The course is designed to bring over the message of the benefits of more rational approaches to macromolecular crystallization. The course will consist of theoretical lectures, seminars as well as practical work and demonstrations (lectures 40%, practical work 50%, seminars 10%). For crystallization experiments, typical recipes using commercial proteins will be used. In addition, students can bring their own proteins and carry out crystallization trials on these during the course.
A poster section is planned in order to encourage participants to present their own work.
Nove Hrady is located in the south of the Czech Republic. The Academic and University Center resides in a very styleful chateau, which provides many facilities such as two lecture halls, laboratories, apartments and a student dormitory.
Speakers and tutors:

  • Terese Bergfors (Upsalla University)
  • Christian Betzel (Univ.-klinikum Hamburg)
  • Christian Biertümpfel (MPI of Biochemistry, Martinsried)
  • Monika Budayova-Spano (UJF-EMBL-CNRS, Grenoble)
  • Jiri Brynda (Academny of Sciences, Prague)
  • Martin Caffrey (Trinity College Dublin)
  • Radka Chaloupkova (Masaryk university, Brno)
  • Naomi E. Chayen (Imperial College London)
  • Allan D’Arcy (Allschwil, Switzerland)
  • Karsten Dierks (Nabitec)
  • Howard Einspahr (IUCr Journal Comission, USA)
  • Juan Manuel Garcia-Ruiz (CSIC-Uni de Granada)
  • Jose A. Gavira (CSIC-Universidad de Granada)
  • Richard Giege (CNRS Strasbourg)
  • Lata Govada (Imperial College London)
  • Ivana Kuta Smatanova (University of South Bohemia)
  • Jeroen Mesters (University of Luebeck)
  • Joe Ng (University of Alabama USA)
  • Marc Pusey (iXpressGenes Inc. Huntsville)
  • Bernard Rupp (Hofkristallamt, Livermore)
  • Claude Sauter (Université de Strasbourg)
  • Stefan Kolek (Douglas Instruments)
  • Ivana Nemcovicova (Bratislava, Slovakia)
  • Lubica Urbanikova (Slovak Academy of Sciences, Bratislava)
  • Pavlina Rezacova (Academy of Sciences, Prague)
  • Da-Chuan Yin (Xian, China)
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4th Prague Protein Spring

The 4th Prague Protein Spring meeting on the subject “Proteins and their Design” is approaching. This theme has been in the spotlight for a few last decades and range of designed proteins increases every year. We would like to reflect not only theoretical and experimental points of view, but we aim to focus on proteins designed for medical purposes associated with diseases or for their biotechnology utilization. The major goal of PPS 2016 meeting is to propose a discussion on the current progress in protein design field and anticipate the future direction of this fascinating discipline of protein science.

We succeeded to recruit great speakers who made significant contributions to the field of protein science and specifically on the protein design subject as well as talented young scientists at the beginning of their careers. See Scientific Program.

We really see the essential characteristics of this meeting in its dedication and focused mission delivered by highly acclaimed scientists and motivated students and their inter-generation interactions. It is high time to register and participate on this exciting event.

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