The XVI Discussions in Structural Molecular Biology and the 3rd User Meeting of CIISB will be held in Nove Hrady, South Bohemia, on 21 – 23 March 2019.
Registration will open in November. Please check this page for the preliminary program.
Jan Dohnalek, on behalf of the organization team
České vysoké učení technické v Praze, Fakulta jaderná a fyzikálně inženýrská a Česká společnost pro strukturní biologii vás zve na přednášku
prof. Kay Diederichs (Univerzita v Kostnici)
Taxonomy of errors and mistakes in X-ray crystallography
Přednáška se bude konat ve PONDĚLÍ dne 12.11.2018 od 10:00 hodin v místnosti ATRIUM v Břehové ulici (FJFI ČVUT, Břehová 7, Praha 1), po přednášce bude následovat představení programů XDS a XDSgui.
Organizační výbor: Jaroslav Bielčík (KF), Ivan Richter (KFE), Tomáš Bílý (KJR), Pavel Šťovíček (KM).
Abstract
Taxonomy of errors and mistakes in X-ray crystallography Crystallography lets us visualize the molecules of life – more than 130.000 structures in the PDB attest to that. But all that glitters is not gold. Some of the concepts developed decades ago now need revision. For example, analysis of crystallographic data quality is still somewhat fixated on values of Rmerge (also called Rsym), and the distinction between accuracy and precision, as well as indicators of unmerged data precision and those of merged data precision is only now starting to be accepted in the community.
The XVI Discussions in Structural Molecular Biology and the 3rd User Meeting of CIISB will be held in Nove Hrady, South Bohemia, on 21 – 23 March 2019.
More details will follow.
Jan Dohnalek, on behalf of the organization team
Minisymposium on Biophysical Methods
24 th September 2018
Location: BIOCEV – Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University (www.biocev.eu), Průmyslová 595, Vestec
Program: Conference Hall (U2.012)
08:30 – 09:00 Gathering and COFFEE Outside conference hall
09:00 – 09:15 Opening and Introduction Dr. Ondřej Vaněk, Charles University
09:15 – 09:50 Measuring Macromolecular Size-Distributions and Interactions at High Concentrations by Sedimentation Velocity Dr. Peter Schuck, NIH, Bethesda (Keynote lecture)
09:50 – 10:15 Studies of High-affinity Protein Interactions Using Analytical Ultracentrifugation with Fluorescence Detection Dr. Huaying Zhao, NIH, Bethesda
10:15 – 10:40 Introduction to Small Angle X‐ray Scattering (SAXS) and Its Use in Studying Protein-Protein Interactions Prof. Tomáš Obšil, Charles University
10:40 – 11:00 TEA & COFFEE BREAK Outside conference hall
11:00 – 11:25 Practical Strategies for the Characterization of Membrane Proteins by AUC Dr. Rodolfo Ghirlando, NIH, Bethesda
11:25 – 11:50 Small Angle Neutron Scattering for Membrane Proteins Dr. Christine Ebel, IBS, CNRS, Grenoble
11:50 – 12:15 Polymer-Encapsulated Nanodiscs for Membrane Biophysics Dr. Sandro Keller, TU Kaiserslautern
12:15 – 13:15 LUNCH BIOCEV Canteen
13:15 – 13:50 Validating Results of Molecular Interaction Measurements Across Different Experimental Platforms Dr. Grzegorz Piszczek, NIH, Bethesda (IUBMB lecture)
13:50 – 14:15 The Happy Partnership of Small-Angle Scattering and Hydrodynamics Prof. Olwyn Byron, University of Glasgow
14:15 – 14:40 ITC as a Tool in Biological Research: What Do We Need to Know? Basics, Planning, Data Treatment and Applications Dr. Margarida Bastos, University of Porto
14:40 – 15:00 TEA & COFFEE BREAK Outside conference hall
15:00 – 15:25 Microscale Thermophoresis and Additional Effects Measured with the NanoTemper Monolith Dr. Arthur Sedivy, VBCF, Vienna Biocenter
15:25 – 15:50 Studying Heat Shock Protein Dynamics and Interactions by Structural Mass Spectrometry Dr. Petr Man, IMB CAS, BIOCEV
15:50 – 16:15 Native mass spectrometry approaches for the investigation of structure and dynamics in complex biomolecular assemblies Dr. Dan Fabris, University at Albany
16:15 – 16:30 TEA & COFFEE BREAK Outside conference hall
16:30 – 19:00 Instrument demo, practical training and discussion (FEBS course only) BIOCEV CMS
19:00 – 22:00 Banquet dinner (FEBS course only) BIOCEV Canteen
20:00 – 22:00 Poster session (FEBS course only) BIOCEV Foyer
The minisymposium is organized as part of the FEBS Practical Course “Hydrodynamic and thermodynamic analysis of biological macromolecules and their interactions” and is co-sponsored by COST Action CA15126 ARBRE-MOBIEU (https://arbre-mobieu.eu) and Instruct.
The lectures are open free of charge – please, invite your students and colleagues as well!!!
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